MICALL1

Across TCGA cell cohorts, MICALL1 mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MICALL1-associated genes across cancer lineages are TBATA, VPREB1, and ETDB. Each is linked with MICALL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MICALL1-to-partner and partner-to-MICALL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBATA grouped by MICALL1-low versus MICALL1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICALL1→partner) and Y-score (partner→MICALL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TBATA →	+0.009	+4.369	<.001	.008	3	1
SOFT_TISSUE	VPREB1 →	+0.052	+4.222	.003	.007	3	1
SOFT_TISSUE	ETDB →	+0.076	+4.222	<.001	.007	3	1
LARGE_INTESTINE	FCN2 →	+0.039	+4.415	<.001	.007	3	1
LARGE_INTESTINE	NUPR2 →	+0.395	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR4F5 →	+0.036	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

TBATA by MICALL1 expression — SOFT_TISSUE

Explore this box plot interactively →