MICAL2

Across TCGA cell cohorts, MICAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,370 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MICAL2-associated GO terms across cancer lineages are Regulation of focal adhesion assembly, Regulation of protein K48-linked ubiquitination, and Regulation of cell-substrate junction assembly. Each is linked with MICAL2 in more than 14 cancer types. Because this analysis shows association rather than direction, both MICAL2-to-partner and partner-to-MICAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of focal adhesion assembly grouped by MICAL2-low versus MICAL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL2→partner) and Y-score (partner→MICAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of focal adhesion assembly →	+0.162	+3.951	<.001	<.001	3	15
BONE	Regulation of protein K48-linked ubiquitination →	+0.154	+3.562	.004	.003	3	15
BONE	Regulation of cell-substrate junction assembly →	+0.162	+3.951	<.001	<.001	3	15
BONE	Regulation of proteolysis →	+0.130	+3.803	<.001	<.001	3	14
BONE	Positive regulation of actin filament bundle assembly →	+0.176	+3.371	<.001	<.001	3	14
KIDNEY	Sarcomere organization →	+0.223	+1.934	.003	.009	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,370 associations by consensus.

Regulation of focal adhesion assembly by MICAL2 expression — BONE

Explore this box plot interactively →