MICAL1

Across TCGA patient cohorts, MICAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,780 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MICAL1-associated genes across cancer lineages are SIGLEC9, LILRB2, and DOCK2. Each is linked with MICAL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MICAL1-to-partner and partner-to-MICAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MICAL1 versus SIGLEC9 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICAL1→partner) and Y-score (partner→MICAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIGLEC9 →	+0.975	+0.372	<.001	<.001	3	10
HNSC	LILRB2 →	+1.176	+0.450	<.001	<.001	3	10
GBM	DOCK2 →	+0.949	+0.376	<.001	.001	3	10
GBM	PIK3R5 →	+0.935	+0.395	<.001	<.001	3	10
GBM	C1orf162 →	+0.777	+0.365	<.001	<.001	3	10
GBM	FCER1G →	+1.165	+0.395	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,780 associations by consensus.

MICAL1 vs SIGLEC9 — GBM

Explore this scatter interactively →