Across TCGA patient cohorts, MICA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,787 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MICA-associated proteins across cancer lineages are ILK, LMNA, and PRDX6_T44. Each is linked with MICA in more than 4 cancer types. Because this analysis shows association rather than direction, both MICA-to-partner and partner-to-MICA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MICA→partner) and Y-score (partner→MICA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ILK →	+0.401	+0.744	<.001	<.001	3	5
GBM	LMNA →	+0.519	+0.693	<.001	.001	3	5
PDAC	PRDX6_T44 →	+0.646	+0.380	<.001	<.001	3	4
UCEC	NEMF →	-0.221	-0.605	<.001	.002	3	4
GBM	VCL →	+0.332	+0.572	.003	.008	2	5
LUAD	CHD7_S2956 →	-0.647	-0.456	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,787 associations by consensus.

Exploration

MICA survival (RNA) · tumor vs normal (RNA) · all MICA data types