Across TCGA patient cohorts, MICA protein abundance is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MICA-associated genes across cancer lineages are HIRA, GZMH, and GZMB. Each is linked with MICA in more than 1 cancer types. Because this analysis shows association rather than direction, both MICA-to-partner and partner-to-MICA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MICA→partner) and Y-score (partner→MICA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HIRA →	+0.526	+0.794	<.001	.003	3	1
LSCC	GZMH →	-1.114	-0.843	.001	.002	3	1
LSCC	GZMB →	-1.214	-0.793	.001	.004	3	1
LSCC	PFDN4 →	+0.688	+0.890	.001	<.001	3	1
LSCC	PRPF6 →	+0.527	+0.699	.004	.002	3	1
LSCC	PRELID3B →	+0.728	+0.771	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

Exploration

MICA survival (RNA) · tumor vs normal (RNA) · all MICA data types