Across TCGA patient cohorts, MIB2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,791 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIB2-associated genes across cancer lineages are DNAJC2, PBK, and FAM162B. Each is linked with MIB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIB2-to-partner and partner-to-MIB2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIB2→partner) and Y-score (partner→MIB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNAJC2 →	-0.522	-0.141	<.001	.001	3	4
LSCC	PBK →	-0.935	-0.127	<.001	.008	3	4
CCRCC	FAM162B →	+1.020	+0.170	<.001	.003	3	4
UCEC	PRKAG2 →	-0.439	-0.130	.002	.003	3	3
OV	MGME1 →	-0.436	-0.246	.001	<.001	3	3
UCEC	USP1 →	-0.382	-0.158	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,791 associations by consensus.

Exploration

MIB2 survival (RNA) · tumor vs normal (RNA) · all MIB2 data types