MIATNB

Across TCGA pan-cancer cohorts, MIATNB RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIATNB’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MIATNB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIATNB is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

LIHC, HNSC, and UCEC are the cancer types where MIATNB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIATNB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.715	<.001	8	view →
HNSC	All	All	+0.305	<.001	7	view →
UCEC	All	All	−0.763	<.001	6	view →
BRCA	All	All	−0.289	<.001	6	view →
CHOL	Male	All	+1.725	<.001	5	view →
THCA	Male	III,IV	−0.281	.023	3	view →
LUSC	Male	All	+0.370	.001	2	view →
LUSC	Male	III,IV	−0.602	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 7 lineages.

MIATNB–LIHC

Open the LIHC breakdown →