MIAT

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIAT mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIAT-associated genes across cancer lineages are RNU6-1252P, RNU6-205P, and RN7SKP135. Each is linked with MIAT in more than 1 cancer types. Because this analysis shows association rather than direction, both MIAT-to-partner and partner-to-MIAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIAT→partner) and Y-score (partner→MIAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1252P →+0.572+8.066<.001.00731
UCECRNU6-205P →+0.562+8.066<.001.00731
UCECRN7SKP135 →+0.173+8.066<.001.00731
UCECMIR3142 →+0.672+8.066<.001.00731
UCECMIR3123 →+0.712+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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