MGST1

Across TCGA patient cohorts, MGST1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,354 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MGST1-associated genes across cancer lineages are SUPT16HP1, DERA, and CP. Each is linked with MGST1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MGST1-to-partner and partner-to-MGST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MGST1 versus SUPT16HP1 in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGST1→partner) and Y-score (partner→MGST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SUPT16HP1 →	+1.687	+0.620	<.001	<.001	3	5
OV	DERA →	+0.501	+0.586	.002	.006	3	4
LSCC	CP →	+2.015	+0.649	<.001	<.001	3	4
LUAD	LMO3 →	+1.193	+0.413	<.001	<.001	3	4
COAD	ALKBH1 →	-0.284	-0.399	.002	<.001	2	4
BRCA	PCNX1 →	-0.465	-0.795	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,354 associations by consensus.

MGST1 vs SUPT16HP1 — LUAD

Explore this scatter interactively →