MGST1

Across TCGA cell cohorts, MGST1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,831 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MGST1-associated genes across cancer lineages are PPARG, TNFRSF21, and RHBDL2. Each is linked with MGST1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MGST1-to-partner and partner-to-MGST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MGST1 versus PPARG in URINARY_TRACT, with a Pearson correlation of 0.47.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGST1→partner) and Y-score (partner→MGST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PPARG →	+2.335	+3.291	<.001	.002	3	8
URINARY_TRACT	TNFRSF21 →	+1.925	+2.461	<.001	.001	3	6
PANCREAS	RHBDL2 →	+2.456	+2.442	<.001	<.001	3	6
BLOOD_Leukemia	TOR4A →	+1.843	+3.302	<.001	<.001	3	6
BLOOD_Leukemia	LTBR →	+3.359	+4.374	<.001	<.001	3	6
LIVER	AKR1B10 →	+5.565	+2.768	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,831 associations by consensus.

MGST1 vs PPARG — URINARY_TRACT

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