MGST1

Across TCGA cell cohorts, MGST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,065 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MGST1-associated GO terms across cancer lineages are Response to lipid hydroperoxide, Glutathione transport, and Regulation of body fluid levels. Each is linked with MGST1 in more than 17 cancer types. Because this analysis shows association rather than direction, both MGST1-to-partner and partner-to-MGST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to lipid hydroperoxide grouped by MGST1-low versus MGST1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGST1→partner) and Y-score (partner→MGST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Response to lipid hydroperoxide →	+2.067	+5.846	<.001	<.001	3	18
BLOOD_Myeloma	Glutathione transport →	+0.146	+3.038	<.001	.001	3	11
OVARY	Regulation of body fluid levels →	+0.081	+3.940	<.001	<.001	3	8
BLOOD_Leukemia	Cellular oxidant detoxification →	+0.086	+3.096	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Establishment or maintenance of transmembrane electrochemical gradient →	+0.199	+2.916	.001	<.001	3	8
LUNG_NSCLC_LUAD	Bile acid and bile salt transport →	+0.072	+2.044	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,065 associations by consensus.

Response to lipid hydroperoxide by MGST1 expression — BLOOD_Leukemia

Explore this box plot interactively →