MGP

Across TCGA cell cohorts, MGP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,011 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MGP-associated GO terms across cancer lineages are Vacuole organization, Export across plasma membrane, and Regulation of translational initiation. Each is linked with MGP in more than 7 cancer types. Because this analysis shows association rather than direction, both MGP-to-partner and partner-to-MGP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by MGP-low versus MGP-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGP→partner) and Y-score (partner→MGP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Vacuole organization →	+0.048	+3.045	.006	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Export across plasma membrane →	-0.101	-0.878	<.001	.009	3	7
BLOOD_Lymphoma	Regulation of translational initiation →	+0.057	+0.174	.005	.008	3	7
SKIN	Negative regulation of myoblast fusion →	+0.084	+2.008	<.001	<.001	3	7
SKIN	CD8-positive, alpha-beta T cell activation →	+0.063	+1.996	.002	.003	3	7
SKIN	Regulation of syncytium formation by plasma membrane fusion →	+0.065	+2.475	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,011 associations by consensus.

Vacuole organization by MGP expression — LIVER

Explore this box plot interactively →