MGLL

Across TCGA cell cohorts, MGLL RNA expression is significantly associated with the go_rna of many other GO terms, with 6,021 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MGLL-associated GO terms across cancer lineages are Actin filament organization, Regulation of actin filament polymerization, and Regulation of actin polymerization or depolymerization. Each is linked with MGLL in more than 15 cancer types. Because this analysis shows association rather than direction, both MGLL-to-partner and partner-to-MGLL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament organization grouped by MGLL-low versus MGLL-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGLL→partner) and Y-score (partner→MGLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament organization →	+0.135	+3.106	<.001	<.001	3	16
OESOPHAGUS	Regulation of actin filament polymerization →	+0.084	+2.203	.004	.001	3	16
BONE	Regulation of actin polymerization or depolymerization →	+0.067	+2.831	.001	.003	3	15
LUNG_NSCLC_LUAD	Regulation of actin filament length →	+0.074	+2.096	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	+1.232	+3.349	.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of actin filament depolymerization →	+0.149	+2.966	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,021 associations by consensus.

Actin filament organization by MGLL expression — BONE

Explore this box plot interactively →