MGAT5

Across TCGA pan-cancer cohorts, MGAT5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MGAT5 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MGAT5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MGAT5 expression acts as an unfavorable survival marker.

LUAD, PDAC, and GBM are the cancer types where MGAT5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.777	0.987	.001	24	view →
PDAC	OS	Median	IV	0.381	0.951	.006	9	view →
GBM	DFS	Tertile	All	0.283	0.494	.020	5	view →
HNSC	DFS	Median	III,IV	0.903	1.000	.004	5	view →
LSCC	DFS	Median	All	0.905	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MGAT5–LUAD (OS)

Open the LUAD breakdown →