MGAT4C

Across TCGA pan-cancer cohorts, MGAT4C Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated MGAT4C data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MGAT4C Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated MGAT4C expression acts as an unfavorable survival marker, although some lineages such as UCEC and SARC show a favorable association.

UCEC, LIHC, and CESC are the cancer types where MGAT4C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.620	.009	22	view →
LIHC	OS	Median	III,IV	0.163	0.654	<.001	21	view →
CESC	OS	Median	III,IV	0.068	0.756	<.001	16	view →
CHOL	DFS	Median	All	0.037	0.486	.001	6	view →
KIRC	OS	Median	All	0.057	0.881	<.001	6	view →
LUAD	DFS	Median	All	0.353	0.682	.008	5	view →
SKCM	DFS	Median	IV	0.134	0.589	.031	3	view →
SARC	DFS	Median	All	1.000	0.327	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

MGAT4C–UCEC (DFS)

Open the UCEC breakdown →