MGAT3

Across TCGA cell cohorts, MGAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,035 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MGAT3-associated GO terms across cancer lineages are Negative regulation of protein catabolic process in the vacuole, Negative regulation of lysosomal protein catabolic process, and Detoxification of copper ion. Each is linked with MGAT3 in more than 8 cancer types. Because this analysis shows association rather than direction, both MGAT3-to-partner and partner-to-MGAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein catabolic process in the vacuole grouped by MGAT3-low versus MGAT3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT3→partner) and Y-score (partner→MGAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein catabolic process in the vacuole →	-0.129	-1.455	<.001	<.001	3	9
BONE	Negative regulation of lysosomal protein catabolic process →	-0.129	-1.455	<.001	<.001	3	9
SOFT_TISSUE	Detoxification of copper ion →	-0.365	-2.016	<.001	<.001	3	8
SOFT_TISSUE	Stress response to copper ion →	-0.365	-2.016	<.001	<.001	3	8
OVARY	Calcium ion transport →	-0.059	-1.742	.003	.001	3	8
LUNG_SCLC	Regulation of G0 to G1 transition →	+0.113	+2.071	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,035 associations by consensus.

Negative regulation of protein catabolic process in the vacuole by MGAT3 expression — BONE

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