MGAT3

Across TCGA cell cohorts, MGAT3 mutation is significantly associated with the mutation status of many other genes, with 4,780 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MGAT3-associated genes across cancer lineages are COL16A1, ZBED4, and B4GALNT4. Each is linked with MGAT3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MGAT3-to-partner and partner-to-MGAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL16A1 grouped by MGAT3-low versus MGAT3-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT3→partner) and Y-score (partner→MGAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	COL16A1 →	+5.095	+4.442	.001	.001	1	5
BLOOD_Lymphoma	ZBED4 →	+6.247	+6.247	<.001	<.001	1	5
LARGE_INTESTINE	B4GALNT4 →	+2.347	+4.392	<.001	<.001	1	5
BLOOD_Lymphoma	GSE1 →	+3.832	+4.316	.002	.002	1	5
STOMACH	LUZP1 →	+3.357	+4.285	.005	.005	1	5
BLOOD_Lymphoma	XRN2 →	+6.247	+6.247	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,780 associations by consensus.

COL16A1 by MGAT3 expression — BREAST

Explore this box plot interactively →