MGAT2

Across TCGA patient cohorts, MGAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MGAT2-associated GO terms across cancer lineages are Regulation of pentose-phosphate shunt, COPII-coated vesicle cargo loading, and Transforming growth factor beta receptor signaling pathway. Each is linked with MGAT2 in more than 27 cancer types. Because this analysis shows association rather than direction, both MGAT2-to-partner and partner-to-MGAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of pentose-phosphate shunt grouped by MGAT2-low versus MGAT2-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT2→partner) and Y-score (partner→MGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Regulation of pentose-phosphate shunt →	+0.065	+0.809	<.001	<.001	3	28
DLBC	COPII-coated vesicle cargo loading →	+0.115	+1.580	<.001	<.001	3	28
UCS	Transforming growth factor beta receptor signaling pathway →	+0.057	+1.320	<.001	<.001	3	27
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.114	+1.927	<.001	<.001	3	27
DLBC	Interleukin-17A-mediated signaling pathway →	+0.065	+1.456	<.001	<.001	3	27
DLBC	Glycosylation →	+0.038	+1.775	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Regulation of pentose-phosphate shunt by MGAT2 expression — UVM

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