MGAT2

Across TCGA patient cohorts, MGAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,216 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MGAT2-associated genes across cancer lineages are RABGAP1, GARNL3, and POGZ. Each is linked with MGAT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MGAT2-to-partner and partner-to-MGAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MGAT2 versus RABGAP1 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT2→partner) and Y-score (partner→MGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RABGAP1 →	-0.370	-0.362	<.001	<.001	3	5
LSCC	GARNL3 →	-0.626	-0.282	<.001	<.001	3	5
BRCA	POGZ →	-0.515	-0.357	<.001	<.001	3	5
BRCA	STAG1 →	-0.532	-0.262	<.001	.007	3	5
BRCA	TET2 →	-0.817	-0.336	<.001	.005	3	5
GBM	SECISBP2 →	-0.358	-0.299	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,216 associations by consensus.

MGAT2 vs RABGAP1 — GBM

Explore this scatter interactively →