MGAT2

Across TCGA cell cohorts, MGAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,149 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MGAT2-associated GO terms across cancer lineages are Protein polymerization, Regulation of early endosome to late endosome transport, and Protein insertion into ER membrane by stop-transfer membrane-anchor sequence. Each is linked with MGAT2 in more than 13 cancer types. Because this analysis shows association rather than direction, both MGAT2-to-partner and partner-to-MGAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polymerization grouped by MGAT2-low versus MGAT2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT2→partner) and Y-score (partner→MGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polymerization →	+0.081	+1.573	<.001	<.001	3	14
BREAST	Regulation of early endosome to late endosome transport →	+0.134	+1.234	<.001	<.001	3	14
KIDNEY	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.124	+1.168	.004	<.001	3	13
BONE	Viral process →	+0.089	+1.633	.001	<.001	3	13
BONE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.104	+1.424	.009	.002	3	13
OESOPHAGUS	Viral gene expression →	+0.106	+1.608	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,149 associations by consensus.

Protein polymerization by MGAT2 expression — UPPER_AERODIGESTIVE_TRACT

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