MGAT2

Across TCGA cell cohorts, MGAT2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MGAT2-associated genes across cancer lineages are MSGN1, CELA3B, and OR4M1. Each is linked with MGAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAT2-to-partner and partner-to-MGAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by MGAT2-low versus MGAT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT2→partner) and Y-score (partner→MGAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	CELA3B →	+0.221	+3.592	<.001	.006	3	1
BREAST	OR4M1 →	+0.018	+5.169	.007	.005	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MSGN1 by MGAT2 expression — LARGE_INTESTINE

Explore this box plot interactively →