MGAT1

Across TCGA pan-cancer cohorts, MGAT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MGAT1 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MGAT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MGAT1 expression acts as an unfavorable survival marker.

PDAC, CCRCC, and LUAD are the cancer types where MGAT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.623	0.862	<.001	83	view →
CCRCC	OS	Quartile	All	0.677	0.992	.001	36	view →
LUAD	DFS	Tertile	All	0.556	1.000	<.001	27	view →
LSCC	OS	Median	All	0.715	0.900	.005	13	view →
COAD	DFS	Tertile	II,III,IV	0.873	1.000	.037	12	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MGAT1–PDAC (DFS)

Open the PDAC breakdown →