MFSD9

Across TCGA cell cohorts, MFSD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,388 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD9-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Phospholipid biosynthetic process, and Endosomal transport. Each is linked with MFSD9 in more than 11 cancer types. Because this analysis shows association rather than direction, both MFSD9-to-partner and partner-to-MFSD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by MFSD9-low versus MFSD9-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD9→partner) and Y-score (partner→MFSD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of DNA-templated transcription, elongation →	+0.093	+1.093	.001	.004	3	12
OVARY	Phospholipid biosynthetic process →	+0.047	+0.824	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.057	+0.716	.008	.003	3	12
STOMACH	Copper ion export →	-0.173	-0.772	<.001	<.001	3	12
OVARY	Vacuolar transport →	+0.056	+0.561	<.001	<.001	3	12
LIVER	Establishment of epithelial cell apical/basal polarity →	-0.231	-0.779	.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,388 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by MFSD9 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →