MFSD9

Across TCGA cell cohorts, MFSD9 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MFSD9-associated genes across cancer lineages are OR10AG1, PABPC1L2A, and OR14A2. Each is linked with MFSD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD9-to-partner and partner-to-MFSD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AG1 grouped by MFSD9-low versus MFSD9-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD9→partner) and Y-score (partner→MFSD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR10AG1 →	+0.043	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	PABPC1L2A →	+0.045	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR14A2 →	+0.022	+5.228	<.001	.005	3	1
LARGE_INTESTINE	TKTL2 →	+0.039	+3.509	<.001	.001	3	1
LARGE_INTESTINE	TFDP3 →	+0.018	+3.196	<.001	<.001	3	1
LARGE_INTESTINE	CENPVL1 →	+0.155	+2.832	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

OR10AG1 by MFSD9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →