MFSD6

Across TCGA cell cohorts, MFSD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,236 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD6-associated GO terms across cancer lineages are Antigen processing and presentation of exogenous peptide antigen via MHC class I, Post-Golgi vesicle-mediated transport, and Ribosome biogenesis. Each is linked with MFSD6 in more than 12 cancer types. Because this analysis shows association rather than direction, both MFSD6-to-partner and partner-to-MFSD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of exogenous peptide antigen via MHC class I grouped by MFSD6-low versus MFSD6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD6→partner) and Y-score (partner→MFSD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Antigen processing and presentation of exogenous peptide antigen via MHC class I →	+0.215	+1.415	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Post-Golgi vesicle-mediated transport →	+0.043	+1.040	.002	.001	3	12
LUNG_SCLC	Ribosome biogenesis →	-0.086	-1.270	.003	.005	3	11
URINARY_TRACT	Serotonin secretion →	+1.656	+1.268	<.001	.005	3	10
LUNG_SCLC	tRNA wobble uridine modification →	-0.106	-1.887	<.001	<.001	3	10
LUNG_SCLC	tRNA wobble position uridine thiolation →	-0.100	-1.315	.005	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,236 associations by consensus.

Antigen processing and presentation of exogenous peptide antigen via MHC class I by MFSD6 expression — OESOPHAGUS

Explore this box plot interactively →