MFSD3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MFSD3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD3-associated genes across cancer lineages are CMP and CD4+ memory T-cells. Each is linked with MFSD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD3-to-partner and partner-to-MFSD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by MFSD3-low versus MFSD3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD3→partner) and Y-score (partner→MFSD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADCMP →+0.025+3.413.013.03431
UCECCD4+ memory T-cells →+0.039+3.202.012.04731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CMP by MFSD3 expression — STAD

Box plot of CMP in MFSD3-low vs MFSD3-high samples in STAD.

Explore this box plot interactively →

Exploration