MFSD3

Across TCGA cell cohorts, MFSD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,272 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MFSD3-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Methylglyoxal metabolic process, and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Each is linked with MFSD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both MFSD3-to-partner and partner-to-MFSD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by MFSD3-low versus MFSD3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD3→partner) and Y-score (partner→MFSD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.223	+1.355	<.001	<.001	3	13
STOMACH	Methylglyoxal metabolic process →	+0.130	+1.002	.001	.007	3	11
OESOPHAGUS	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.060	+1.286	.006	.002	3	11
OESOPHAGUS	Methylglyoxal catabolic process →	+0.201	+1.233	.001	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.148	-1.176	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.148	-1.176	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,272 associations by consensus.

Pre-mRNA catabolic process by MFSD3 expression — BONE

Explore this box plot interactively →