Across TCGA patient cohorts, MFSD2B mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD2B-associated genes across cancer lineages are GMP, aDC, and DC. Each is linked with MFSD2B in more than 2 cancer types. Because this analysis shows association rather than direction, both MFSD2B-to-partner and partner-to-MFSD2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD2B→partner) and Y-score (partner→MFSD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GMP →	+0.044	+2.806	.016	.040	3	3
UCEC	aDC →	+0.089	+2.177	.007	.035	3	1
UCEC	DC →	+0.024	+2.082	.009	.038	3	1
UCEC	Endothelial cells →	-0.043	-2.657	.012	.006	3	1
UCEC	mv Endothelial cells →	-0.026	-2.947	.016	.036	3	1
UCEC	Plasma cells →	-0.022	-1.957	.025	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

MFSD2B survival (RNA) · tumor vs normal (RNA) · all MFSD2B data types