Across TCGA cell cohorts, MFSD2B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,593 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD2B-associated GO terms across cancer lineages are SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, Regulation of myoblast fusion, and Positive regulation of cellular response to transforming growth factor beta stimulus. Each is linked with MFSD2B in more than 7 cancer types. Because this analysis shows association rather than direction, both MFSD2B-to-partner and partner-to-MFSD2B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD2B→partner) and Y-score (partner→MFSD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.049	+0.251	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.093	+0.202	<.001	<.001	2	8
LARGE_INTESTINE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.070	+0.095	.003	.005	3	7
LARGE_INTESTINE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.070	+0.095	.003	.005	3	7
BLOOD_Leukemia	Negative regulation of gene expression, epigenetic →	+0.048	+0.954	<.001	.007	2	8
BREAST	Positive regulation of transcription initiation by RNA polymerase II →	+0.054	+0.145	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,593 associations by consensus.

Exploration

MFSD2B survival (RNA) · tumor vs normal (RNA) · all MFSD2B data types