Across TCGA cell cohorts, MFSD2B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFSD2B-associated genes across cancer lineages are EXOC1L, GJD2, and OR1L6. Each is linked with MFSD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD2B-to-partner and partner-to-MFSD2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD2B→partner) and Y-score (partner→MFSD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	EXOC1L →	+0.366	+3.459	.001	.004	3	1
LARGE_INTESTINE	GJD2 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR1D2 →	+0.011	+4.022	<.001	.006	3	1
LARGE_INTESTINE	SLC15A5 →	+0.013	+4.415	<.001	<.001	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

MFSD2B survival (RNA) · tumor vs normal (RNA) · all MFSD2B data types