Across TCGA pan-cancer cohorts, MFSD1P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MFSD1P1’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where MFSD1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types MFSD1P1 is over-expressed in tumor, although a few such as THCA and ESCA show the opposite, repressed pattern.
THCA and ESCA are the cancer types where MFSD1P1 tumor–normal differential expression is most reproducible.