MFSD14B

Across TCGA patient cohorts, MFSD14B mutation is significantly associated with the RNA expression of many other genes, with 4,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD14B-associated genes across cancer lineages are SNX3P1Y, RNA5SP66, and PSMB7P1. Each is linked with MFSD14B in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD14B-to-partner and partner-to-MFSD14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by MFSD14B-low versus MFSD14B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD14B→partner) and Y-score (partner→MFSD14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.065	+3.834	<.001	.007	3	2
BLCA	RNA5SP66 →	+0.278	+7.640	<.001	.009	3	2
BLCA	PSMB7P1 →	+0.104	+7.640	<.001	.009	3	2
STAD	FAM197Y1 →	+0.085	+5.226	<.001	.003	3	2
STAD	RNU7-34P →	+0.879	+5.396	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.803	+2.426	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,840 associations by consensus.

SNX3P1Y by MFSD14B expression — UCEC

Explore this box plot interactively →