MFSD14B

Across TCGA cell cohorts, MFSD14B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,765 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MFSD14B-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Positive regulation of chromosome condensation, and Immunoglobulin heavy chain V-D-J recombination. Each is linked with MFSD14B in more than 15 cancer types. Because this analysis shows association rather than direction, both MFSD14B-to-partner and partner-to-MFSD14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by MFSD14B-low versus MFSD14B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD14B→partner) and Y-score (partner→MFSD14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Proteasome regulatory particle assembly →	+0.137	+1.000	.001	<.001	3	16
KIDNEY	Positive regulation of chromosome condensation →	+0.239	+1.117	<.001	.002	3	14
PANCREAS	Immunoglobulin heavy chain V-D-J recombination →	+0.192	+0.684	<.001	<.001	3	14
KIDNEY	Positive regulation of mRNA 3'-end processing →	+0.148	+1.293	<.001	<.001	3	12
KIDNEY	Negative regulation of cell cycle process →	+0.052	+0.961	<.001	.004	3	11
PANCREAS	Positive regulation of cell cycle →	+0.066	+0.728	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,765 associations by consensus.

Proteasome regulatory particle assembly by MFSD14B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →