MFSD12

Across TCGA patient cohorts, MFSD12 mutation is significantly associated with the RNA expression of many other genes, with 448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD12-associated genes across cancer lineages are MIR5787, ATG4A, and TTC19. Each is linked with MFSD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD12-to-partner and partner-to-MFSD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5787 grouped by MFSD12-low versus MFSD12-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD12→partner) and Y-score (partner→MFSD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR5787 →	+0.242	+3.098	<.001	.008	3	2
UCEC	ATG4A →	+0.520	+3.218	.003	.009	3	2
UCEC	TTC19 →	+0.533	+3.210	.006	.009	3	2
UCEC	RPA1 →	+0.609	+3.606	.008	.001	3	2
COAD	RNU7-81P →	+0.222	+4.109	<.001	.007	3	2
UCEC	PARP3 →	+0.809	+3.219	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 448 associations by consensus.

MIR5787 by MFSD12 expression — SKCM

Explore this box plot interactively →