MFSD12

Across TCGA patient cohorts, MFSD12 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD12-associated genes across cancer lineages are CD8+ Tcm, Astrocytes, and Tregs. Each is linked with MFSD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD12-to-partner and partner-to-MFSD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by MFSD12-low versus MFSD12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD12→partner) and Y-score (partner→MFSD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.022	+2.198	.016	.039	3	2
LIHC	Astrocytes →	+0.164	+5.479	<.001	.043	3	1
SKCM	Tregs →	+0.011	+2.564	.004	.022	3	1
COAD	Preadipocytes →	+0.042	+2.847	<.001	.007	3	1
COAD	Th2 cells →	+0.223	+3.000	.019	.037	3	1
UCEC	HSC →	+0.109	+3.008	.040	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CD8+ Tcm by MFSD12 expression — UCEC

Explore this box plot interactively →