MFSD12

Across TCGA cell cohorts, MFSD12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,857 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MFSD12-associated GO terms across cancer lineages are Pigment metabolic process involved in pigmentation, Cysteine transmembrane transport, and Cysteine transport. Each is linked with MFSD12 in more than 19 cancer types. Because this analysis shows association rather than direction, both MFSD12-to-partner and partner-to-MFSD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pigment metabolic process involved in pigmentation grouped by MFSD12-low versus MFSD12-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD12→partner) and Y-score (partner→MFSD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Pigment metabolic process involved in pigmentation →	+0.352	+1.109	<.001	<.001	3	20
PANCREAS	Cysteine transmembrane transport →	+0.324	+1.478	<.001	<.001	3	15
PANCREAS	Cysteine transport →	+0.324	+1.478	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.142	+1.004	<.001	<.001	3	14
URINARY_TRACT	Positive regulation of establishment of T cell polarity →	+0.205	+1.058	<.001	<.001	3	12
SOFT_TISSUE	Multi-pass transmembrane protein insertion into ER membrane →	+0.141	+1.089	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,857 associations by consensus.

Pigment metabolic process involved in pigmentation by MFSD12 expression — LUNG_SCLC

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