MFSD10

Across TCGA cell cohorts, MFSD10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,636 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD10-associated GO terms across cancer lineages are Clathrin coat disassembly, Transcription pausing by RNA polymerase II, and Positive regulation of CAMKK-AMPK signaling cascade. Each is linked with MFSD10 in more than 14 cancer types. Because this analysis shows association rather than direction, both MFSD10-to-partner and partner-to-MFSD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Clathrin coat disassembly grouped by MFSD10-low versus MFSD10-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD10→partner) and Y-score (partner→MFSD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Clathrin coat disassembly →	+0.127	+1.138	<.001	<.001	3	15
BONE	Transcription pausing by RNA polymerase II →	+0.173	+1.070	<.001	<.001	3	14
SKIN	Positive regulation of CAMKK-AMPK signaling cascade →	+0.527	+1.230	.003	<.001	3	13
BONE	Regulation of aggrephagy →	+0.143	+0.998	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular protein transport →	+0.071	+1.067	<.001	<.001	3	11
BREAST	Cellular response to bile acid →	+0.914	+0.925	.005	.003	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,636 associations by consensus.

Clathrin coat disassembly by MFSD10 expression — BLOOD_Lymphoma

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