MFSD1

Across TCGA pan-cancer cohorts, MFSD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MFSD1 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MFSD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MFSD1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, LSCC, and HNSC are the cancer types where MFSD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.926	0.511	.010	18	view →
LSCC	DFS	Quartile	II,III,IV	0.424	0.843	.027	2	view →
HNSC	DFS	Median	II,III,IV	0.969	0.899	.040	2	view →
CCRCC	DFS	Quartile	III,IV	0.405	0.778	.024	1	view →
GBM	DFS	Median	All	0.650	0.818	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MFSD1–LUAD (OS)

Open the LUAD breakdown →