MFSD1

Across TCGA cell cohorts, MFSD1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFSD1-associated genes across cancer lineages are C20orf173, DYNAP, and NCR1. Each is linked with MFSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD1-to-partner and partner-to-MFSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf173 grouped by MFSD1-low versus MFSD1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD1→partner) and Y-score (partner→MFSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C20orf173 →	+0.070	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	DYNAP →	+0.059	+5.452	.004	<.001	3	1
STOMACH	NCR1 →	+0.074	+4.129	<.001	.007	3	1
STOMACH	IZUMO3 →	+0.577	+4.129	<.001	.007	3	1
LARGE_INTESTINE	TKTL2 →	+0.054	+4.187	<.001	.002	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

C20orf173 by MFSD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →