MFNG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MFNG protein abundance is significantly associated with the RNA expression of many other genes, with 15,746 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MFNG-associated genes across cancer lineages are SLC8A3, ARHGAP5, and RASSF2. Each is linked with MFNG in more than 1 cancer types. Because this analysis shows association rather than direction, both MFNG-to-partner and partner-to-MFNG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFNG versus SLC8A3 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFNG→partner) and Y-score (partner→MFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSLC8A3 →+0.300+0.496.003.00132
LSCCARHGAP5 →-0.686-0.693.001<.00132
LSCCRASSF2 →+1.131+0.752.002<.00132
LSCCPPP1R16B →+0.848+0.507<.001<.00132
LUADCD40LG →+0.725+0.534<.001<.00132
LSCCRASL12 →+0.718+0.501<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,746 associations by consensus.

MFNG vs SLC8A3 — LUAD

Per-sample scatter of MFNG vs SLC8A3 in LUAD (Pearson r = 0.42).

Explore this scatter interactively →

Exploration