MFN1

Across TCGA patient cohorts, MFN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,340 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MFN1-associated proteins across cancer lineages are FXR1, PAK2, and UBXN7. Each is linked with MFN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MFN1-to-partner and partner-to-MFN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFN1 versus FXR1 in LSCC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MFN1→partner) and Y-score (partner→MFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FXR1 →	+0.605	+0.978	<.001	<.001	3	9
OV	PAK2 →	+0.302	+0.569	.001	<.001	3	6
LSCC	UBXN7 →	+0.582	+0.862	<.001	<.001	3	6
LSCC	ACTL6A →	+0.405	+0.931	<.001	<.001	3	6
LSCC	ABCF3 →	+0.383	+0.724	<.001	<.001	3	6
LSCC	GMPS →	+0.562	+0.719	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,340 associations by consensus.

MFN1 vs FXR1 — LSCC

Explore this scatter interactively →