MFGE8

Across TCGA patient cohorts, MFGE8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,151 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MFGE8-associated genes across cancer lineages are UACA, MSRB3, and PRELP. Each is linked with MFGE8 in more than 7 cancer types. Because this analysis shows association rather than direction, both MFGE8-to-partner and partner-to-MFGE8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFGE8 versus UACA in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFGE8→partner) and Y-score (partner→MFGE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UACA →	+0.690	+0.549	<.001	<.001	3	8
COAD	MSRB3 →	+1.127	+0.648	<.001	<.001	3	8
COAD	PRELP →	+1.491	+0.581	<.001	<.001	3	8
COAD	MYL9 →	+1.159	+0.395	<.001	<.001	3	7
OV	SYDE1 →	+0.931	+0.506	<.001	.003	3	7
BRCA	ACTA2 →	+1.013	+0.691	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,151 associations by consensus.

MFGE8 vs UACA — GBM

Explore this scatter interactively →