MFGE8

Across TCGA cell cohorts, MFGE8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,237 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MFGE8-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, Protein stabilization, and Negative regulation of myoblast fusion. Each is linked with MFGE8 in more than 15 cancer types. Because this analysis shows association rather than direction, both MFGE8-to-partner and partner-to-MFGE8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by MFGE8-low versus MFGE8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFGE8→partner) and Y-score (partner→MFGE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maintenance of protein localization in organelle →	+0.135	+1.892	.001	.002	3	16
LARGE_INTESTINE	Protein stabilization →	+0.068	+2.788	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.111	+1.279	<.001	<.001	3	14
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+3.204	<.001	<.001	3	14
BONE	Apoptotic cell clearance →	+0.258	+2.339	<.001	<.001	3	14
BONE	Golgi vesicle transport →	+0.071	+2.667	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,237 associations by consensus.

Maintenance of protein localization in organelle by MFGE8 expression — BONE

Explore this box plot interactively →