Across TCGA pan-cancer cohorts, MFAP5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MFAP5 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MFAP5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MFAP5 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LSCC, CCRCC, and PDAC are the cancer types where MFAP5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.520	0.813	.004	34	view →
CCRCC	DFS	Median	III,IV	0.105	0.928	.003	33	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	11	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MFAP5 tumor-vs-normal RNA expression · all MFAP5 data types