MFAP5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MFAP5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFAP5-associated genes across cancer lineages are OR56A5, TNP1, and OR10W1. Each is linked with MFAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP5-to-partner and partner-to-MFAP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP5→partner) and Y-score (partner→MFAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTOR56A5 →+0.045+4.736<.001.00931
LARGE_INTESTINETNP1 →+0.172+5.415<.001.00431
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
BLOOD_LeukemiaGUCA2A →+0.052+5.969<.001.00131
BLOOD_LeukemiaKRTAP7-1 →+0.095+5.539<.001.00331
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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