Across TCGA cell cohorts, MFAP3L mutation is significantly associated with the mutation status of many other genes, with 3,793 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFAP3L-associated genes across cancer lineages are SEL1L2, ELMO3, and RP1. Each is linked with MFAP3L in more than 2 cancer types. Because this analysis shows association rather than direction, both MFAP3L-to-partner and partner-to-MFAP3L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP3L→partner) and Y-score (partner→MFAP3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SEL1L2 →	+5.560	+4.736	.003	.003	1	3
BLOOD_Leukemia	ELMO3 →	+3.338	+4.083	.003	.003	1	3
BLOOD_Leukemia	RP1 →	+3.338	+4.083	.003	.003	1	3
BLOOD_Leukemia	ACAD10 →	+3.145	+3.932	.004	.004	1	3
BLOOD_Leukemia	AKAP8L →	+3.560	+4.247	.002	.002	1	3
LARGE_INTESTINE	HSPA5 →	+3.584	+3.007	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,793 associations by consensus.

Exploration

MFAP3L survival (RNA) · tumor vs normal (RNA) · all MFAP3L data types