MFAP3

Across TCGA patient cohorts, MFAP3 mutation is significantly associated with the RNA expression of many other genes, with 1,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFAP3-associated genes across cancer lineages are RN7SL25P, VTRNA2-2P, and MIR6075. Each is linked with MFAP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MFAP3-to-partner and partner-to-MFAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL25P grouped by MFAP3-low versus MFAP3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP3→partner) and Y-score (partner→MFAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL25P →	+0.167	+3.211	.003	.005	3	4
CESC	VTRNA2-2P →	+0.361	+4.601	.001	.004	3	2
CESC	MIR6075 →	+0.525	+4.276	.001	.008	3	2
UCEC	CEBPA-DT →	-0.530	-1.552	.003	.005	3	2
UCEC	CIRBP-AS1 →	+0.426	+2.534	<.001	<.001	3	2
HNSC	RNU1-17P →	+0.333	+5.435	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,799 associations by consensus.

RN7SL25P by MFAP3 expression — SKCM

Explore this box plot interactively →