MFAP3

Across TCGA cell cohorts, MFAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,001 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFAP3-associated GO terms across cancer lineages are Protein polyubiquitination, Import into nucleus, and Protein localization to nucleus. Each is linked with MFAP3 in more than 14 cancer types. Because this analysis shows association rather than direction, both MFAP3-to-partner and partner-to-MFAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by MFAP3-low versus MFAP3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP3→partner) and Y-score (partner→MFAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein polyubiquitination →	+0.064	+1.081	.002	<.001	3	15
LIVER	Import into nucleus →	+0.065	+0.768	.001	.002	3	14
OESOPHAGUS	Protein localization to nucleus →	+0.079	+1.022	<.001	<.001	3	14
SKIN	Regulation of DNA-templated transcription elongation →	+0.072	+1.201	<.001	<.001	3	14
OESOPHAGUS	Regulation of transcription elongation by RNA polymerase II →	+0.076	+1.132	.009	.003	3	14
LARGE_INTESTINE	Regulation of translational initiation →	+0.081	+0.738	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,001 associations by consensus.

Protein polyubiquitination by MFAP3 expression — STOMACH

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