MFAP3

Across TCGA cell cohorts, MFAP3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MFAP3-associated genes across cancer lineages are OPRPN and PATE4. Each is linked with MFAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP3-to-partner and partner-to-MFAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by MFAP3-low versus MFAP3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP3→partner) and Y-score (partner→MFAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPRPN →	+0.060	+5.087	<.001	.004	3	1
LARGE_INTESTINE	PATE4 →	+0.041	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OPRPN by MFAP3 expression — URINARY_TRACT

Explore this box plot interactively →