MFAP1

Across TCGA patient cohorts, MFAP1 mutation is significantly associated with the RNA expression of many other genes, with 1,437 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFAP1-associated genes across cancer lineages are TRDV3, LINC02616, and RNA5SP336. Each is linked with MFAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP1-to-partner and partner-to-MFAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDV3 grouped by MFAP1-low versus MFAP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP1→partner) and Y-score (partner→MFAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRDV3 →	+0.860	+3.605	<.001	.005	3	2
CESC	LINC02616 →	+0.408	+3.428	<.001	.001	3	2
CESC	RNA5SP336 →	+0.112	+4.252	.002	.006	3	2
CESC	RNU6-258P →	+0.145	+4.579	<.001	.003	3	2
CESC	RNU5E-9P →	+0.164	+3.984	<.001	.009	3	2
UCEC	RNU6-1318P →	+0.356	+2.980	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,437 associations by consensus.

TRDV3 by MFAP1 expression — CESC

Explore this box plot interactively →